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Dr. Pappolla served as a consultant for the National Institutes of Health in the United States including being a chartered member of numerous study sections for over 25 years and as a full professor or faculty at several medical schools (LSU New Orleans, Mount Sinai Medical School in New York City, University of Texas) where he taught Neurosciences to medical students and medical residents for over 20 years. Currently, he holds a hybrid academic-private practice position in the Houston area Dr. Pappolla's training included 3 complete medical residencies and 2 fellowships (Neurology, Clinical Pathology, Anatomic Pathology, Neuropathology, Pain Medicine), a PhD in human aging with a postdoc/sabbatical in molecular biology followed by over almost 30 years of a combined academic and private practice. He holds active board certifications in these 5 areas (Neurology, Clinical Pathology, Anatomic Pathology, Neurology, Pain Medicine). Some of his research work is cited in several thousand textbooks worldwide, with many papers reaching from 300 to over 1000 citations in peer reviewed journals.