Chemical signalling in CNS

Chemical signalling in CNS Photo

Neurotransmitters are generated mainly at the region of [re-synaptic clefts which are produced at post synaptic regions with excitation and inhibition actions. Non-neuronal cells release neurotropic factors that act mainly on kinase-linked receptors (tyrosine) which have regulatory action on genome expression. It also controls growth of phenotype characteristics. Neurons communicate with the help of chemical and electrical signalling which allows signals driven capabilities for conduction in end to end cells. This conduction process takes place inside the neuronal cell at the gaps present in between which is termed as Synapse where communication between neurons occurs or takes place in between the tiny gaps of synapse. Neuro Chemical transmission majorly takes place in between the pre-synaptic and post-synaptic regions of neurons which are extended and inter converted with their tendency from initial to final stages. Alteration in post synaptic neurons occurs when a neurotransmitter molecule binds to the receptor proteins. Ligand-gated ion channels and G-protein couple receptors allow rapid ion flow to the outer cell membrane regions. The neurotransmitter molecule binds to the receptor proteins and alters post synaptic neuronal function. Neurotrophins and Steroidal hormones mainly influence the function and development of the neurons and neuronal membranes.

  • Mode of signaling
  • Types of receptors
  • Signaling transduction
  • Classification of signaling pathways
  • Components of cell signaling
  • Integration of Genomic, Transcriptomic Data
  • Functioning of impulse and signals

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